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Severe Eczema Vaccinatum in a Household Contact of a Smallpox Vaccinee
Author(s) -
Surabhi B Vora,
Inger K. Damon,
Vincent A. Fulginiti,
Stephen G. Weber,
Madelyn Kahana,
Sarah L. Stein,
Susan I. Gerber,
Sylvia GarciaHouchins,
Edith Lederman,
Dennis E. Hruby,
Limone Collins,
Dorothy E. Scott,
Kenneth W. Thompson,
John Barson,
Russell L. Regnery,
Christine M. Hughes,
Robert S. Daum,
Li Yu,
Hui Zhao,
Scott K. Smith,
Zach Braden,
Kevin L. Karem,
Victoria A. Olson,
Whitni Davidson,
Giliane S. Trindade,
Tove’ C. Bolken,
Robert Jordan,
Debbie Tien,
John Marcinak
Publication year - 2008
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/587668
Subject(s) - medicine , vaccinia , smallpox vaccine , smallpox , vaccination , orthopoxvirus , adverse effect , immunology , pediatrics , dermatology , biochemistry , chemistry , gene , recombinant dna
We report the first confirmed case of eczema vaccinatum in the United States related to smallpox vaccination since routine vaccination was discontinued in 1972. A 28-month-old child with refractory atopic dermatitis developed eczema vaccinatum after exposure to his father, a member of the US military who had recently received smallpox vaccine. The father had a history of inactive eczema but reportedly reacted normally to the vaccine. The child's mother also developed contact vaccinia infection.

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