Ascaris lumbricoides–Induced Interleukin‐10 Is Not Associated with Atopy in Schoolchildren in a Rural Area of the Tropics | Zendy

Philip J. Cooper | Zendy; Edward Mitre | Zendy; Ana L. Moncayo | Zendy; Martha Chico | Zendy; Maritza Vaca | Zendy; Thomas B. Nutman | Zendy

Open Access

Ascaris lumbricoides–Induced Interleukin‐10 Is Not Associated with Atopy in Schoolchildren in a Rural Area of the Tropics

Author(s) -

Philip J. Cooper,

Edward Mitre,

Ana L. Moncayo,

Martha Chico,

Maritza Vaca,

Thomas B. Nutman

Publication year - 2008

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/586904

Subject(s) - ascaris lumbricoides , atopy , ascaris , immunology , helminths , helminthiasis , biology , allergy , interleukin 4 , immunoglobulin e , trichuris trichiura , environmental health , medicine , cytokine , antibody

In areas where intestinal helminth infections are endemic, infections by these parasites may protect against skin test-measured reactivity to allergens, and it has been suggested that interleukin (IL)-10 may mediate this effect. This study investigated whether IL-10 and populations of IL-10+ T cells may modulate atopy in children living in an area where intestinal helminth infections are endemic.

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