Doxycycline Treatment ofBrugia malayi–Infected Persons Reduces Microfilaremia and Adverse Reactions after Diethylcarbamazine and Albendazole Treatment | Zendy

Taniawati Supali | Zendy; Yenny Djuardi | Zendy; Kenneth Pfarr | Zendy; Heri Wibowo | Zendy; Mark J. Taylor | Zendy; Achim Hoerauf | Zendy; Jeanine J. HouwingDuistermaat | Zendy; Maria Yazdanbakhsh | Zendy; Erliyani Sartono | Zendy

Open Access

Doxycycline Treatment ofBrugia malayi–Infected Persons Reduces Microfilaremia and Adverse Reactions after Diethylcarbamazine and Albendazole Treatment

Author(s) -

Taniawati Supali,

Yenny Djuardi,

Kenneth Pfarr,

Heri Wibowo,

Mark J. Taylor,

Achim Hoerauf,

Jeanine J. HouwingDuistermaat,

Maria Yazdanbakhsh,

Erliyani Sartono

Publication year - 2008

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/586753

Subject(s) - diethylcarbamazine , albendazole , doxycycline , medicine , placebo , lymphatic filariasis , adverse effect , brugia malayi , filariasis , gastroenterology , surgery , antibiotics , immunology , pathology , biology , alternative medicine , helminths , microbiology and biotechnology

The efficacy of doxycycline for treating the causal agent of human lymphatic filariasis, Brugia malayi, is unknown. Standard treatment with diethylcarbamazine-albendazole is associated with adverse reactions. We assessed whether doxycycline alone or in combination with diethylcarbamazine-albendazole would lead to sustained amicrofilaremia and reduced incidence of adverse reactions.

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