Host Polymorphisms in Interleukin 4, Complement Factor H, and C‐Reactive Protein Associated with Nasal Carriage ofStaphylococcus aureusand Occurrence of Boils
Author(s) -
Marieke Emonts,
André G. Uitterlinden,
Jan Nouwen,
Isabella Kardys,
Moniek P.M. de Maat,
Damian C. Melles∗,
Jacqueline C.M. Witteman,
Paulus T. V. M. de Jong,
Henri A. Verbrugh,
Albert Hofman,
Peter W. M. Hermans,
Alex van Belkum
Publication year - 2008
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/533501
Subject(s) - staphylococcus aureus , carriage , genotype , biology , genotyping , haplotype , microbiology and biotechnology , staphylococcal infections , amplified fragment length polymorphism , immunology , genetics , gene , medicine , bacteria , genetic diversity , pathology , population , environmental health
Staphylococcus aureus is capable of persistently colonizing the vestibulum nasi. We hypothesized that polymorphisms in host inflammatory response genes and genetic variation in S. aureus contribute to susceptibility to S. aureus carriage and infection.
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