Two Quantitative Trait Loci Influence Whipworm(Trichuris trichiura)Infection in a Nepalese Population
Author(s) -
Sarah WilliamsBlangero,
John L. VandeBerg,
Janardan Subedi,
Bharat Jha,
Tom Dyer,
John Blangero
Publication year - 2008
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/533493
Subject(s) - trichuris trichiura , quantitative trait locus , biology , genetics , trichuris , population , odds ratio , heritability , helminths , medicine , immunology , gene , environmental health , ascaris lumbricoides
Whipworm (Trichuris trichiura) infection is a soil-transmitted helminth infection that affects >1 billion people. It is a serious public health problem in many developing countries and can result in deficits in growth and cognitive development. In a follow-up study of significant heritability for whipworm infection, we conducted the first genome scan for quantitative trait loci (QTL) influencing the heritability of susceptibility to this important parasitic disease.
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