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Timing of Antibiotic Prophylaxis for Primary Total Knee Arthroplasty Performed during Ischemia
Author(s) -
Álex Soriano,
Guillem Bori,
S. García-Ramiro,
J.C. Martínez-Pastor,
Teresa Miana,
Carles Codina,
Francesc Maculé,
M. Basora,
José Antônio Baddini Martínez,
Josep Riba,
S. Suso,
Josep Mensa
Publication year - 2008
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/529145
Subject(s) - medicine , total knee arthroplasty , antibiotics , ischemia , arthroplasty , antibiotic prophylaxis , surgery , anesthesia , microbiology and biotechnology , biology
There is no clinical trial analyzing the best moment to infuse an antibiotic during knee arthroplasty performed during ischemia. We designed a single-center, randomized, double-blind, placebo-controlled trial to evaluate whether antibiotic therapy should be administered before tourniquet inflation or just before tourniquet deflation.

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