Comparison of Pneumococcal Conjugate Polysaccharide and Free Polysaccharide Vaccines in Elderly Adults: Conjugate Vaccine Elicits Improved Antibacterial Immune Responses and Immunological Memory | Zendy

A de Roux | Zendy; Beate Schmöele-Thoma | Zendy; George R. Siber | Zendy; Jill Hackell | Zendy; A. Kuhnke | Zendy; N. Ahlers | Zendy; Shirley Baker | Zendy; Ahmad Razmpour | Zendy; Emilio A. Emini | Zendy; Philip Fernsten | Zendy; William C. Gruber | Zendy; Stephen Lockhart | Zendy; Olaf Burkhardt | Zendy; Tobias Welte | Zendy; H. Lode | Zendy

Open Access

Comparison of Pneumococcal Conjugate Polysaccharide and Free Polysaccharide Vaccines in Elderly Adults: Conjugate Vaccine Elicits Improved Antibacterial Immune Responses and Immunological Memory

Author(s) -

A de Roux,

Beate Schmöele-Thoma,

George R. Siber,

Jill Hackell,

A. Kuhnke,

N. Ahlers,

Shirley Baker,

Ahmad Razmpour,

Emilio A. Emini,

Philip Fernsten,

William C. Gruber,

Stephen Lockhart,

Olaf Burkhardt,

Tobias Welte,

H. Lode

Publication year - 2008

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/529142

Subject(s) - medicine , conjugate , immunization , immune system , conjugate vaccine , immunology , pneumococcal conjugate vaccine , pneumococcal polysaccharide vaccine , antibody , polysaccharide , streptococcus pneumoniae , microbiology and biotechnology , pneumococcal disease , antibiotics , biology , mathematical analysis , biochemistry , mathematics

High functional antibody responses, establishment of immunologic memory, and unambiguous efficacy in infants suggest that an initial dose of conjugated pneumococcal polysaccharide (PnC) vaccine may be of value in a comprehensive adult immunization strategy.

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