Persistent Bordetella bronchiseptica Pneumonia in an Immunocompetent Infant and Genetic Comparison of Clinical Isolates with Kennel Cough Vaccine Strains | Zendy

Barbara Rath | Zendy; Karen B. Register | Zendy; J.S. Wall | Zendy; Danny Sokol | Zendy; Russell B. Van Dyke | Zendy

Open Access

Persistent Bordetella bronchiseptica Pneumonia in an Immunocompetent Infant and Genetic Comparison of Clinical Isolates with Kennel Cough Vaccine Strains

Author(s) -

Barbara Rath,

Karen B. Register,

J.S. Wall,

Danny Sokol,

Russell B. Van Dyke

Publication year - 2008

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/528858

Subject(s) - bordetella bronchiseptica , medicine , bordetella pertussis , pneumonia , clearance , virology , bordetella , whooping cough , immunology , vaccination , biology , bacteria , genetics , urology

An infant who experienced recurrent episodes of respiratory failure received a diagnosis of pertussis on the basis of immunofluorescence testing, but culture revealed macrolide-resistant Bordetella bronchiseptica. Genetic analysis demonstrated that the child was not infected with a kennel cough vaccine strain, although the family's dog had recently been vaccinated. The infection cleared with imipenem therapy.

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