Placental Hypoxia during Placental Malaria
Author(s) -
Philippe Boeuf,
Aimee Tan,
Cleofé Romagosa,
Jane Radford,
Victor Mwapasa,
Malcolm E. Molyneux,
Steven R. Meshnick,
Nicholas H. Hunt,
Stephen J. Rogerson
Publication year - 2008
Publication title -
the journal of infectious diseases
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/526521
Subject(s) - syncytiotrophoblasts , biology , laser capture microdissection , syncytiotrophoblast , placenta , hypoxia (environmental) , placental growth factor , vascular endothelial growth factor , monocyte , malaria , immunology , gene expression , andrology , endocrinology , fetus , cancer research , gene , pregnancy , medicine , genetics , chemistry , organic chemistry , oxygen , vegf receptors
Placental malaria causes fetal growth retardation (FGR), which has been linked epidemiologically to placental monocyte infiltrates. We investigated whether parasite or monocyte infiltrates were associated with placental hypoxia, as a potential mechanism underlying malarial FGR.
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