Vitamin D Deficiency Is Associated with Tuberculosis and Latent Tuberculosis Infection in Immigrants from Sub-Saharan Africa
Author(s) -
Katherine B. Gibney,
Lachlan MacGregor,
Karin Leder,
Joseph Torresi,
Caroline Marshall,
Peter R. Ebeling,
BeverleyAnn Biggs
Publication year - 2008
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/525268
Subject(s) - tuberculosis , latent tuberculosis , medicine , mycobacterium tuberculosis , immigration , vitamin d and neurology , immunology , vitamin d deficiency , active tuberculosis , pathology , geography , archaeology
Among African immigrants in Melbourne, Victoria, Australia, we demonstrated lower geometric mean vitamin D levels in immigrants with latent tuberculosis infection than in those with no Mycobacterium tuberculosis infection (P=.007); such levels were also lower in immigrants with tuberculosis or past tuberculosis than in those with latent tuberculosis infection (P=.001). Higher vitamin D levels were associated with lower probability of any M. tuberculosis infection (P=.001) and lower probability of tuberculosis or past tuberculosis (compared with latent tuberculosis infection; P=.001).
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