Blood Monocytes Harbor HIV Type 1 Strains with Diversified Phenotypes Including Macrophage‐Specific CCR5 Virus
Author(s) -
Youg Xu,
Haiying Zhu,
Carrie K. Wilcox,
Angélique van’t Wout,
Thomas Andrus,
Nicholas Llewellyn,
Leonidas Stamatatos,
James I. Mullins,
Lawrence Corey,
Tuofu Zhu
Publication year - 2008
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/524847
Subject(s) - monocyte , biology , virology , phenotype , virus , macrophage , tropism , seroconversion , cxcr4 , tissue tropism , immunology , chemokine , immune system , gene , in vitro , genetics
Recent studies have shown that blood monocytes harbor human immunodeficiency virus type 1 (HIV-1) variants that are genotypically distinguishable from those in CD4(+) T cells. However, the biological function of monocyte-derived HIV-1 remains unclear.
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