Activation of the Coagulation Cascade in Patients with Leptospirosis | Zendy

Wirongrong Chierakul | Zendy; Panutsaya Tientadakul | Zendy; Yupin Suputtamongkol | Zendy; Vanaporn Wuthiekanun | Zendy; Kriangsak Phimda | Zendy; R. Limpaiboon | Zendy; Nisarat Opartkiattikul | Zendy; Nicholas J. White | Zendy; Sharon J. Peacock | Zendy; N. P. Day | Zendy

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Activation of the Coagulation Cascade in Patients with Leptospirosis

Author(s) -

Wirongrong Chierakul,

Panutsaya Tientadakul,

Yupin Suputtamongkol,

Vanaporn Wuthiekanun,

Kriangsak Phimda,

R. Limpaiboon,

Nisarat Opartkiattikul,

Nicholas J. White,

Sharon J. Peacock,

N. P. Day

Publication year - 2007

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/524664

Subject(s) - leptospirosis , medicine , disseminated intravascular coagulation , fibrinogen , partial thromboplastin time , hemostasis , sepsis , antithrombin , gastroenterology , prothrombin time , coagulopathy , coagulation , immunology , pathology , heparin

Disseminated intravascular coagulation (DIC) is common among patients with sepsis. Leptospirosis is an important cause of sepsis in tropical areas, and pulmonary hemorrhage associated with thrombocytopenia is the major cause of death, but the coagulopathy in severe leptospirosis has not been further characterized. The aim of this study was to evaluate coagulation factors and the presence of DIC in patients with leptospirosis in northeast Thailand.

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