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CD4+(and Not CD25+) T Cells Are the Predominant Interleukin‐10–Producing Cells in the Circulation of Filaria‐Infected Patients
Author(s) -
Edward Mitre,
Daniel Chien,
Thomas B. Nutman
Publication year - 2007
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/524301
Subject(s) - il 2 receptor , immunology , biology , interleukin 3 , peripheral blood mononuclear cell , flow cytometry , cd8 , interleukin 4 , interleukin , cd14 , cd19 , immune system , interleukin 2 , microbiology and biotechnology , cytokine , t cell , in vitro , biochemistry
Interleukin (IL)-10 plays an important role in down-regulating the immune response to filarial parasites. The goal of this study was to characterize the predominant cellular source of IL-10 in human filarial infections.

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