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Rapid Virologic Response: A New Milestone in the Management of Chronic Hepatitis C
Author(s) -
Fred Poordad,
K. Rajender Reddy,
Paul Martin
Publication year - 2007
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/523585
Subject(s) - medicine , ribavirin , regimen , hepatitis c virus , pegylated interferon , hepatitis c , viral load , milestone , immunology , gastroenterology , virus , archaeology , history
Rapid virologic response (RVR), defined as an undetectable serum hepatitis C virus (HCV) RNA level at week 4 of treatment, is emerging as an important milestone in the treatment of patients who have chronic hepatitis C by use of pegylated interferon-alfa and ribavirin--the current standard of care. This assessment is being used to individualize treatment duration, which is currently recommended as 48 weeks in patients infected with HCV genotype 1 (G1) and 24 weeks in those infected with HCV G2 or G3.

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