In Vitro Production of Panton-Valentine Leukocidin among Strains of Methicillin-Resistant Staphylococcus aureus Causing Diverse Infections | Zendy

S. M. Hamilton | Zendy; Amy E. Bryant | Zendy; Karen C. Carroll | Zendy; Vivian Marie Lockary | Zendy; Yanju Ma | Zendy; Eric R. McIndoo | Zendy; Loren G. Miller | Zendy; Françoise PerdreauRemington | Zendy; John Pullman | Zendy; G. F. Risi | Zendy; Daniel B. Salmi | Zendy; Dennis L. Stevens | Zendy

Open Access

In Vitro Production of Panton-Valentine Leukocidin among Strains of Methicillin-Resistant Staphylococcus aureus Causing Diverse Infections

Author(s) -

S. M. Hamilton,

Amy E. Bryant,

Karen C. Carroll,

Vivian Marie Lockary,

Yanju Ma,

Eric R. McIndoo,

Loren G. Miller,

Françoise PerdreauRemington,

John Pullman,

G. F. Risi,

Daniel B. Salmi,

Dennis L. Stevens

Publication year - 2007

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/523581

Subject(s) - panton–valentine leukocidin , staphylococcus aureus , leukocidin , microbiology and biotechnology , methicillin resistant staphylococcus aureus , medicine , staphylococcal infections , sccmec , toxin , virology , biology , bacteria , genetics

Community-acquired methicillin-resistant Staphylococcus aureus strains have recently been associated with severe necrotizing infections. Greater than 75% of these strains carry the genes for Panton-Valentine leukocidin (PVL), suggesting that this toxin may mediate these severe infections. However, to date, studies have not provided evidence of toxin production.

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