Infection of Hamsters with Historical and Epidemic BI Types ofClostridium difficile | Zendy

Nadia Razaq | Zendy; Susan P. Sambol | Zendy; Kristin Nagaro | Zendy; Walter E. Zukowski | Zendy; Adam Cheknis | Zendy; Stuart Johnson | Zendy; Dale N. Gerding | Zendy

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Infection of Hamsters with Historical and Epidemic BI Types ofClostridium difficile

Author(s) -

Nadia Razaq,

Susan P. Sambol,

Kristin Nagaro,

Walter E. Zukowski,

Adam Cheknis,

Stuart Johnson,

Dale N. Gerding

Publication year - 2007

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/523106

Subject(s) - clostridium difficile , clindamycin , virulence , outbreak , microbiology and biotechnology , inoculation , hamster , mesocricetus , biology , virology , medicine , antibiotics , immunology , biochemistry , gene

North American and European hospitals have reported outbreaks of Clostridium difficile-associated disease with unexpectedly high mortality caused by a newly recognized group of C. difficile strains, group BI. Our objective was to compare, in hamsters, the virulence of a historical nonepidemic BI type, BI1, with that of 2 recent epidemic BI types, BI6 and BI17, and with that of 2 standard toxigenic strains, K14 and 630.

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