Evolution of the Extensively Drug-Resistant F15/LAM4/KZN Strain of Mycobacterium tuberculosis in KwaZulu-Natal, South Africa | Zendy

Manormoney Pillay | Zendy; A. Willem Sturm | Zendy

Open Access

Evolution of the Extensively Drug-Resistant F15/LAM4/KZN Strain of Mycobacterium tuberculosis in KwaZulu-Natal, South Africa

Author(s) -

Manormoney Pillay,

A. Willem Sturm

Publication year - 2007

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/522987

Subject(s) - tuberculosis , mycobacterium tuberculosis , streptomycin , drug resistance , medicine , multiple drug resistance , strain (injury) , virology , drug resistant tuberculosis , isoniazid , microbiology and biotechnology , biology , antibiotics , pathology

Although several hot spots of multidrug-resistant tuberculosis have been identified on the African continent, extensive drug resistance (XDR) has not been reported until recently, when a large number of XDR cases were identified in KwaZulu-Natal. The majority of the patients involved were infected with the same strain of Mycobacterium tuberculosis (F15/LAM4/KZN). We report this strain's development from multidrug resistance to XDR.

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