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The World Health Organization advocates 2-3 doses of sulfadoxine-pyrimethamine (SP) for intermittent preventive treatment of malaria (SP IPTp). The optimal number of doses and the consequences of single-dose therapy remain unclear.

Inferiority of Single‐Dose Sulfadoxine‐Pyrimethamine Intermittent Preventive Therapy for Malaria during Pregnancy among HIV‐Positive Zambian Women