Advanced Multifocal Tuberculous Spondylitis without Disk Involvement and with Multidrug-Resistant Bacilli | Zendy

A Neher | Zendy; Wouter H. Kopp | Zendy; Giovanni Berna | Zendy; James A. Frank | Zendy; Martin Kohlhäufl | Zendy

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Advanced Multifocal Tuberculous Spondylitis without Disk Involvement and with Multidrug-Resistant Bacilli

Author(s) -

A Neher,

Wouter H. Kopp,

Giovanni Berna,

James A. Frank,

Martin Kohlhäufl

Publication year - 2007

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/521931

Subject(s) - medicine , spondylitis , tuberculosis , bacilli , sputum , multiple drug resistance , drug resistance , antibiotics , surgery , pathology , microbiology and biotechnology , bacteria , genetics , biology , ankylosing spondylitis

In this brief report, we describe a 23-year-old immunocompetent Nigerian patient with extensive multifocal tuberculous spondylitis without disk involvement. Cultures of sputum samples and biopsy samples from the L4 vertebra were positive for tuberculosis; drug-susceptibility testing of the isolates revealed multidrug resistance. Treatment with second-line drugs resulted in an excellent interim outcome after 6 months, without the need for surgical intervention.

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