Effect of Pneumococcal Conjugate Vaccine on Nasopharyngeal Colonization among Immunized and Unimmunized Children in a Community‐Randomized Trial | Zendy

Katherine L. O’Brien | Zendy; Eugene V. Millar | Zendy; Elizabeth R. Zell | Zendy; Melinda A. Bronsdon | Zendy; Robert Weatherholtz | Zendy; Raymond Reid | Zendy; Jocelyn Becenti | Zendy; Sheri Kvamme | Zendy; Cynthia G. Whitney | Zendy; Mathuram Santosham | Zendy

Open Access

Effect of Pneumococcal Conjugate Vaccine on Nasopharyngeal Colonization among Immunized and Unimmunized Children in a Community‐Randomized Trial

Author(s) -

Katherine L. O’Brien,

Eugene V. Millar,

Elizabeth R. Zell,

Melinda A. Bronsdon,

Robert Weatherholtz,

Raymond Reid,

Jocelyn Becenti,

Sheri Kvamme,

Cynthia G. Whitney,

Mathuram Santosham

Publication year - 2007

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/521833

Subject(s) - medicine , pneumococcal conjugate vaccine , vaccination , colonization , odds ratio , confidence interval , serotype , pneumococcal infections , randomized controlled trial , vaccine efficacy , immunology , streptococcus pneumoniae , biology , microbiology and biotechnology , antibiotics

Pneumococcal conjugate vaccines (PCVs) prevent vaccine serotype (VT) invasive disease; nonvaccine serotype (NVT) disease increases modestly. The impact of PCV on nasopharyngeal (NP) colonization is essential to understanding disease effects.

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