The Association between Mannan‐Binding Lectin Gene Polymorphism and Clinical Leprosy: New Insight into an Old Paradigm | Zendy

Iara Messias-Reason | Zendy; Angelica Beate Winter Boldt | Zendy; Anna Carolina Moraes Braga | Zendy; Ewalda Von Rosen Seeling Stahlke | Zendy; Luciasser Dornelles | Zendy; Lilian PereiraFerrari | Zendy; Peter G. Kremsner | Zendy; Jürgen F. J. Kun | Zendy

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The Association between Mannan‐Binding Lectin Gene Polymorphism and Clinical Leprosy: New Insight into an Old Paradigm

Author(s) -

Iara Messias-Reason,

Angelica Beate Winter Boldt,

Anna Carolina Moraes Braga,

Ewalda Von Rosen Seeling Stahlke,

Luciasser Dornelles,

Lilian PereiraFerrari,

Peter G. Kremsner,

Jürgen F. J. Kun

Publication year - 2007

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/521627

Subject(s) - leprosy , mannan binding lectin , mannan , biology , genetics , gene , lectin , immunology , polymorphism (computer science) , c type lectin , allele , computational biology , polysaccharide , biochemistry

Mannan-binding lectin (MBL), a soluble protein of innate immunity, is known to play a role in pathogen recognition and clearance. For more than a decade, it has been proposed that MBL deficiency may be protective against intracellular pathogens, such as Mycobacterium leprae.

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