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Mannan-binding lectin (MBL), a soluble protein of innate immunity, is known to play a role in pathogen recognition and clearance. For more than a decade, it has been proposed that MBL deficiency may be protective against intracellular pathogens, such as Mycobacterium leprae.

The Association between Mannan‐Binding Lectin Gene Polymorphism and Clinical Leprosy: New Insight into an Old Paradigm