Open AccessThe Association betweenTrichomonas vaginalisInfection and Level of Vaginal Lactobacilli, in Nonpregnant Women
Author(s) -
Michelle Torok,
William C. Miller,
Marcia M. Hobbs,
Pia D. M. MacDonald,
Peter A. Leone,
Jane R. Schwebke,
Arlene C. Seña
Publication year - 2007
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/521307
Subject(s) - trichomoniasis , trichomonas vaginalis , medicine , odds ratio , confidence interval , gynecology , vagina , trichomonas vaginitis , sexually transmitted disease , obstetrics , trichomonas , vaginal disease , vaginitis , immunology , human immunodeficiency virus (hiv) , syphilis , surgery
The effect that vaginal lactobacilli have on trichomoniasis is not known. At 3 clinics for treatment of sexually transmitted disease, we recruited 521 female patients with trichomoniasis and 176 control subjects. All participants underwent physical examinations and testing for sexually transmitted infection and completed questionnaires. Low levels of vaginal lactobacilli were associated with trichomoniasis (odds ratio [OR], 2.2 [95% confidence interval {CI}, 1.4-3.2]). After adjustment for covariables, this association remained in women with a higher educational level (OR, 4.6 [95% CI, 2.2-9.5]) but not in women with a lower educational level (OR, 1.6 [95% CI, 0.7-3.4]). Vaginal lactobacilli may be associated with trichomoniasis in women with higher levels of education or a related behavioral factor.
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