Cross‐Protection against H5N1 Influenza Virus Infection Is Afforded by Intranasal Inoculation with Seasonal Trivalent Inactivated Influenza Vaccine
Author(s) -
Takeshi Ichinohe,
Shinichi Tamura,
Akira Kawaguchi,
Ai Ninomiya,
Masaki Imai,
Shigeyuki Itamura,
Takato Odagiri,
Masato Tashiro,
Hidehiro Takahashi,
Hirofumi Sawa,
William M. Mitchell,
David R. Strayer,
William A. Carter,
Joe Chiba,
Takeshi Kurata,
Tetsutaro Sata,
Hideki Hasegawa
Publication year - 2007
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/521304
Subject(s) - virology , nasal administration , inoculation , influenza a virus subtype h5n1 , virus , influenza vaccine , orthomyxoviridae , influenza a virus , microbiology and biotechnology , medicine , biology , immunology
Avian H5N1 influenza A virus is an emerging pathogen with the potential to cause substantial human morbidity and mortality. We evaluated the ability of currently licensed seasonal influenza vaccine to confer cross-protection against highly pathogenic H5N1 influenza virus in mice.
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