Comparison of 2 Antibiotics That Inhibit Protein Synthesis for the Treatment of Infection withYersinia pestisDelivered by Aerosol in a Mouse Model of Pneumonic Plague
Author(s) -
Henry S. Heine,
Arnold Louie,
Fritz Sörgel,
Jennifer Bassett,
Lynda Miller,
Lawrence J. Sullivan,
Martina KinzigSchippers,
George L. Drusano
Publication year - 2007
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/520547
Subject(s) - gentamicin , yersinia pestis , neutropenia , levofloxacin , doxycycline , antibiotics , medicine , aminoglycoside , microbiology and biotechnology , pharmacology , in vivo , immunology , chemotherapy , biology , biochemistry , virulence , gene
Intentional release of Yersinia pestis will likely be propagated by aerosol exposure. We explored the effects of neutropenia on the outcome of doxycycline and gentamicin therapy.
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