Human Granulocytic Ehrlichiosis in Northern California: Two Case Descriptions with Genetic Analysis of the Ehrlichiae | Zendy

Janet E. Foley | Zendy; Leta CrawfordMiksza | Zendy; J. Stephen Dumler | Zendy; Carol Glaser | Zendy; JoonSeok Chae | Zendy; Elaine Yeh | Zendy; David Schnurr | Zendy; Ron Hood | Zendy; Willard Hunter | Zendy; John E. Madigan | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Human Granulocytic Ehrlichiosis in Northern California: Two Case Descriptions with Genetic Analysis of the Ehrlichiae

Author(s) -

Janet E. Foley,

Leta CrawfordMiksza,

J. Stephen Dumler,

Carol Glaser,

JoonSeok Chae,

Elaine Yeh,

David Schnurr,

Ron Hood,

Willard Hunter,

John E. Madigan

Publication year - 1999

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/520220

Subject(s) - ehrlichiosis , myalgia , malaise , medicine , tick , virology , polymerase chain reaction , immunology , gene , biology , genetics

We report two cases of human granulocytic ehrlichiosis (HGE) that occurred in northern California in summer 1998. Patients had fever, malaise, and myalgia, reported tick bites, had moderate thrombocytopenia, and had normal or slightly elevated liver enzyme activities. Ehrlichial inclusions were observed in the blood of one patient, and HGE-agent DNA was amplified by PCR from both patients. Genetically, the strains resembled horse isolates from northern California. The close spatial and temporal proximity of the two new cases may be due to a nidus of infection in the area or heightened surveillance by local physicians.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research