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The Effects of Maternal Malaria and HIV‐1 Infection on the Effort to Eliminate Neonatal Tetanus
Author(s) -
William J. Moss,
Neal A. Halsey
Publication year - 2007
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/519849
Subject(s) - clostridium tetani , tetanus , neonatal tetanus , malaria , medicine , microbiology and biotechnology , cerebral malaria , biology , human immunodeficiency virus (hiv) , immunology , virology , plasmodium falciparum , vaccination
genic strains of Clostridium tetani and has been estimated to have caused 213,000 deaths globally in 2002 [1]. An estimated 180,000 of these deaths occurred in neonates, and an additional 15,000-30,000 deaths occurred in women during the early postpartum period. C. tetani is a spore-forming, anaerobic bacillus capable of producing several toxins, including tetanospasmin, which blocks inhibitory neurotransmitters in the central nervous

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