Thrombocytopenia and Release of Activated von Willebrand Factor during EarlyPlasmodium falciparumMalaria | Zendy

Quirijn de Mast | Zendy; Evelyn Groot | Zendy; Peter J. Lenting | Zendy; Philip G. de Groot | Zendy; Matthew B. B. McCall | Zendy; Robert W. Sauerwein | Zendy; Rob Fijnheer | Zendy; André van der Ven | Zendy

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Thrombocytopenia and Release of Activated von Willebrand Factor during EarlyPlasmodium falciparumMalaria

Author(s) -

Quirijn de Mast,

Evelyn Groot,

Peter J. Lenting,

Philip G. de Groot,

Matthew B. B. McCall,

Robert W. Sauerwein,

Rob Fijnheer,

André van der Ven

Publication year - 2007

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/519844

Subject(s) - von willebrand factor , agglutination (biology) , malaria , plasmodium falciparum , immunology , platelet , secretion , platelet activation , medicine , virology , biology , antigen

Thrombocytopenia occurs early during malarial infection, but its underlying mechanism is unclear. Secretion of von Willebrand factor (vWF) occurs on endothelial cell activation, and it plays an important role in platelet agglutination.

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