Long‐Term Persistence of Transmitted HIV Drug Resistance in Male Genital Tract Secretions: Implications for Secondary Transmission
Author(s) -
Davey M. Smith,
Joseph K. Wong,
Hai Shao,
George K. Hightower,
H. Stephanie,
Joseph M. Moreno,
Caroline Ignacio,
Simon D. W. Frost,
Douglas D. Richman,
Susan J. Little
Publication year - 2007
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/519164
Subject(s) - semen , drug resistance , biology , hiv drug resistance , virology , persistence (discontinuity) , transmission (telecommunications) , sexual transmission , sex organ , lentivirus , immunology , drug , virus , human immunodeficiency virus (hiv) , physiology , viral disease , medicine , viral load , microbicide , pharmacology , microbiology and biotechnology , genetics , antiretroviral therapy , engineering , geotechnical engineering , electrical engineering
Transmitted drug-resistant HIV slowly reverts in the blood to drug-sensitive virus. The environment of the male genital tract (MGT) may result in even slower rates of reversion to drug susceptibility.
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