Systemic Inflammation in Patients with Chronic Obstructive Pulmonary Disease Who Are Colonized with Pneumocystis jiroveci | Zendy

Enrique J. Calderón | Zendy; L. Rivero | Zendy; N. Respaldiza | Zendy; Rubén Morilla | Zendy; M. Montes-Cano | Zendy; Vicente Friaza | Zendy; Fernando Muñoz-Lobato | Zendy; J.M. Varela | Zendy; Francisco J. Medrano | Zendy; C. de la Horra | Zendy

Open Access

Systemic Inflammation in Patients with Chronic Obstructive Pulmonary Disease Who Are Colonized with Pneumocystis jiroveci

Author(s) -

Enrique J. Calderón,

L. Rivero,

N. Respaldiza,

Rubén Morilla,

M. Montes-Cano,

Vicente Friaza,

Fernando Muñoz-Lobato,

J.M. Varela,

Francisco J. Medrano,

C. de la Horra

Publication year - 2007

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/518989

Subject(s) - medicine , proinflammatory cytokine , pulmonary disease , immunology , systemic inflammation , inflammation , copd , disease , lung function , respiratory disease , pulmonary function testing , pneumocystis jirovecii , lung , human immunodeficiency virus (hiv)

In chronic obstructive pulmonary disease, high levels of airway and systemic inflammatory markers are associated with a faster decrease in lung function. Our study shows that patients colonized by Pneumocystis jiroveci have higher proinflammatory cytokine levels than do noncolonized patients. This suggests that Pneumocystis may play a role in disease progression.

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