Open AccessMethotrexate Treatment for Type 1 (Reversal) Leprosy Reactions
Author(s) -
G. Biosca,
Sonia Casallo,
Rogelio LópezVélez
Publication year - 2007
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/518699
Subject(s) - medicine , leprosy , methotrexate , lepromatous leprosy , adverse effect , dermatology , dapsone , surgery
Corticosteroids are the drugs of choice for treatment of type 1 leprosy reactions, but when these agents cannot be used because of their adverse effects, alternative treatments are needed. We report the first case, to our knowledge, of a type 1 leprosy reaction that was successfully treated with methotrexate in a patient intolerant to corticosteroids who had borderline lepromatous leprosy.
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