HLA Polymorphisms and Cervical Human Papillomavirus Infection in a Cohort of Montreal University Students
Author(s) -
Salaheddin M. Mahmud,
Keira Robinson,
Harriet Richardson,
PierrePaul Tellier,
Alex Ferenczy,
Michel Roger,
François Coutlée,
Eduardo L. Franco
Publication year - 2007
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/518612
Subject(s) - hpv infection , odds ratio , human leukocyte antigen , allele , cervical cancer , polymerase chain reaction , immunology , biology , papillomaviridae , cohort , oncology , medicine , genetics , cancer , gene , antigen
Only a minority of women with human papillomavirus (HPV) infection eventually develop cervical cancer, which suggests that host immune mechanisms play a role in the disease. HLA polymorphisms have been linked to the risk of cervical cancer, but very little is known about the role that they play in the acquisition and persistence of HPV infection.
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