Helicobacter pyloriInduces Up‐Regulation of the Epidermal Growth Factor Receptor in AGS Gastric Epithelial Cells | Zendy

Sarah Keates | Zendy; Andrew C. Keates | Zendy; Kianoosh Katchar | Zendy; Richard M. Peek | Zendy; Ciarán P. Kelly | Zendy

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Helicobacter pyloriInduces Up‐Regulation of the Epidermal Growth Factor Receptor in AGS Gastric Epithelial Cells

Author(s) -

Sarah Keates,

Andrew C. Keates,

Kianoosh Katchar,

Richard M. Peek,

Ciarán P. Kelly

Publication year - 2007

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/518440

Subject(s) - transactivation , epidermal growth factor receptor , helicobacter pylori , autocrine signalling , biology , cancer research , carcinogenesis , microbiology and biotechnology , epidermal growth factor , receptor , cancer , gene expression , gene , biochemistry , genetics

Helicobacter pylori infection increases the risk of gastric carcinogenesis. The aim of the present study was to determine whether H. pylori could up-regulate the expression of the epidermal growth factor receptor (EGFR), a critical gene in the carcinogenic process.

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