Clinical, Immunological, and Epidemiological Importance of Antituberculosis T Cell Responses in HIV-Infected Africans | Zendy

Molebogeng X. Rangaka | Zendy; Lavanya Diwakar | Zendy; Ronnett Seldon | Zendy; Gilles Van Cutsem | Zendy; Graeme Meintjes | Zendy; Chelsea Morroni | Zendy; P. Mouton | Zendy; Muki Shey | Zendy; Gary Maartens | Zendy; Katalin A. Wilkinson | Zendy; Robert J. Wilkinson | Zendy

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Clinical, Immunological, and Epidemiological Importance of Antituberculosis T Cell Responses in HIV-Infected Africans

Author(s) -

Molebogeng X. Rangaka,

Lavanya Diwakar,

Ronnett Seldon,

Gilles Van Cutsem,

Graeme Meintjes,

Chelsea Morroni,

P. Mouton,

Muki Shey,

Gary Maartens,

Katalin A. Wilkinson,

Robert J. Wilkinson

Publication year - 2007

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/518234

Subject(s) - tuberculosis , tuberculin , medicine , immunology , antigen , mycobacterium tuberculosis , interferon gamma , virology , latent tuberculosis , cytokine , pathology

Human immunodeficiency virus (HIV)-associated tuberculosis is a major cause of mortality in Africa. The assay of T cell interferon- gamma released in response to antigens of greater specificity than purified protein derivative is a useful improvement over the Mantoux tuberculin skin test, but few studies have evaluated interferon-gamma secretion in HIV-infected individuals.

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