Thalidomide Therapy for the Treatment of Hypertrophic Herpes Simplex Virus--Related Genitalis in HIV-Infected Individuals | Zendy

A Holmes | Zendy; Máirín E. McMenamin | Zendy; F Mulcahy | Zendy; Colm Bergin | Zendy

Open Access

Thalidomide Therapy for the Treatment of Hypertrophic Herpes Simplex Virus--Related Genitalis in HIV-Infected Individuals

Author(s) -

A Holmes,

Máirín E. McMenamin,

F Mulcahy,

Colm Bergin

Publication year - 2007

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/517513

Subject(s) - medicine , cidofovir , foscarnet , thalidomide , herpes genitalis , virology , herpes simplex virus , famciclovir , sexually transmitted disease , malignancy , immunology , viral disease , dermatology , human immunodeficiency virus (hiv) , virus , herpesviridae , genital herpes , multiple myeloma , syphilis

Hypertrophic genital herpes is a disfiguring manifestation of a common infection seen in immunocompromised hosts that can be clinically mistaken for malignancy. We review the literature and describe hypertrophic genital herpes in a human immunodeficiency virus-positive patient receiving antiretroviral therapy. Treatment with valacyclovir, cidofovir, and foscarnet failed, but thalidomide treatment was successful.

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