Recovery of Cytomegalovirus and Herpes Simplex Virus from Upper and Lower Genital Tract Specimens Obtained from Women with Pelvic Inflammatory Disease | Zendy

Lorraine Clarke | Zendy; Ann Duerr | Zendy; Kristen R. Yeung | Zendy; Suzanne Brockman | Zendy; Cibele Barbosa | Zendy; Milagros A. Macasaet | Zendy

Open Access

Recovery of Cytomegalovirus and Herpes Simplex Virus from Upper and Lower Genital Tract Specimens Obtained from Women with Pelvic Inflammatory Disease

Author(s) -

Lorraine Clarke,

Ann Duerr,

Kristen R. Yeung,

Suzanne Brockman,

Cibele Barbosa,

Milagros A. Macasaet

Publication year - 1997

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/517268

Subject(s) - pelvic inflammatory disease , herpes simplex virus , ectopic pregnancy , cytomegalovirus , tubal ligation , medicine , fallopian tube , chlamydia trachomatis , uterus , salpingitis , virus , herpesviridae , gynecology , pregnancy , viral disease , virology , biology , population , environmental health , family planning , research methodology , genetics

Lower genital tract specimens and endometrial biopsies from 147 women with pelvic inflammatory disease (PID) and surgical specimens (fallopian tubes, ovaries, or both) from 22 women with PID and 37 women without PID were cultured for cytomegalovirus (CMV) and herpes simplex virus (HSV), as well as for organisms commonly associated with PID. CMV was isolated from 39 cervical or endometrial samples from 30 (20.4%) of 147 women with PID and from ovaries or fallopian tubes from 5 (22.7%) of 22 women with PID, but CMV was not recovered from surgical specimens obtained from 37 women undergoing surgery for tubal ligation, ectopic pregnancy, or other gynecologic conditions (P = .005). HSV was isolated from cervical samples obtained from 5 (3.4%) of 147 women with PID but not from any endometrial or surgical specimens. These data suggest that CMV, but not HSV, may contribute to the pathogenesis of PID in some patients.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research