Incidence of Hepatitis B Virus Infection in the United States, 1976–1994: Estimates from the National Health and Nutrition Examination Surveys
Author(s) -
Patrick J. Coleman,
Geraldine M. McQuillan,
Linda A. Moyer,
Stephen B. Lambert,
Harold S. Margolis
Publication year - 1998
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/515696
Subject(s) - national health and nutrition examination survey , incidence (geometry) , virology , medicine , hepatitis a virus , environmental health , hepatitis b virus , virus , population , physics , optics
Precise estimates of the incidence of hepatitis B virus (HBV) infection are required to assess the impact of immunization and other prevention strategies in the United States. Race- and age-specific prevalence data obtained from the second and third National Health and Nutrition Examination Surveys (NHANES II, 1976-1980, and NHANES III, 1988-1994) were used to estimate the annual incidence of HBV infection by catalytic modeling. During the period covered by NHANES II, an estimated 323,462 persons were infected annually, and 334,863 were infected annually during the period covered by NHANES III. No statistically significant declines in prevalence of HBV infection occurred between the two surveys, a period during which hepatitis B vaccination targeted only limited numbers of high-risk adults.
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