Asymptomatic Sexually Transmitted Disease Prevalence in Four Military Populations: Application of DNA Amplification Assays forChlamydiaand Gonorrhea Screening | Zendy

Stephanie K. Brodine | Zendy; Mary–Ann Shafer | Zendy; Richard A. Shaffer | Zendy; Cherrie B. Boyer | Zendy; Shan D. Putnam | Zendy; F. Stephen Wignall | Zendy; Richard J. Thomas | Zendy; Barbara Bales | Zendy; Julius Schachter | Zendy

Open Access

Asymptomatic Sexually Transmitted Disease Prevalence in Four Military Populations: Application of DNA Amplification Assays forChlamydiaand Gonorrhea Screening

Author(s) -

Stephanie K. Brodine,

Mary–Ann Shafer,

Richard A. Shaffer,

Cherrie B. Boyer,

Shan D. Putnam,

F. Stephen Wignall,

Richard J. Thomas,

Barbara Bales,

Julius Schachter

Publication year - 1998

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/515685

Subject(s) - asymptomatic , medicine , gonorrhea , ligase chain reaction , chlamydia , population , sexually transmitted disease , pelvic inflammatory disease , chlamydia trachomatis , gynecology , virology , obstetrics , immunology , polymerase chain reaction , biology , environmental health , syphilis , genetics , multiplex polymerase chain reaction , human immunodeficiency virus (hiv) , gene

The prevalence of asymptomatic chlamydial and gonococcal infections in male and female military populations was determined using urine-based ligase chain reaction DNA amplification assays (DAAs). Cross-sectional surveys in four military settings revealed an overall prevalence of asymptomatic chlamydial infection of 4.2% (56/1338). This included 3.4% (21/618) of Western Pacific shipboard US Marine Corps enlisted men; 5.2% (21/406) of male marines shore-based in Okinawa, Japan; 2.7% (5/183) of female enlisted US Navy subtender personnel in dry dock; and 6.9% (9/131) of shore-based female naval personnel in San Diego. No gonococcal infections were detected. All subjects were treated within 2 weeks of screening; none of them had progressed to symptomatic disease. General population-based screening for asymptomatic sexually transmitted diseases, and in particular chlamydial infection, can be successfully implemented using urine-based DAA tests. Benefits are maximized in a population in which compliance for follow-up therapy is high.

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