Rapidly Evolving Hepatitis C Virus–Related Cirrhosis in a Human Immunodeficiency Virus–Infected Patient Receiving Triple Antiretroviral Therapy | Zendy

Hervé Zylberberg | Zendy; Gilles Pialoux | Zendy; Françoise Carnot | Zendy; Alain Landau | Zendy; Christian Bréchot | Zendy; S. Pol | Zendy

Open Access

Rapidly Evolving Hepatitis C Virus–Related Cirrhosis in a Human Immunodeficiency Virus–Infected Patient Receiving Triple Antiretroviral Therapy

Author(s) -

Hervé Zylberberg,

Gilles Pialoux,

Françoise Carnot,

Alain Landau,

Christian Bréchot,

S. Pol

Publication year - 1998

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/514987

Subject(s) - medicine , hepatitis c virus , virology , hepatitis c , cirrhosis , protease inhibitor (pharmacology) , virus , human immunodeficiency virus (hiv) , immunology , viral disease , immune system , antiretroviral therapy , viral load

Triple antiretroviral therapy combining reverse transcriptase and protease inhibitors modifies the prognosis of human immunodeficiency virus (HIV) infection, with dramatic improvement in immune status. The precise impact, if any, of anti-HIV triple therapy on hepatitis C virus (HCV) infection is unknown. We describe an unusual case of rapidly evolving HCV-related cirrhosis that paralleled restoration of immune status in an HIV-infected patient and discuss the possible link between such a severe course of hepatitis C and anti-HIV triple therapy.

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