Strain Prevalence, Rather than Innate Virulence Potential, Is the Major Factor Responsible for an Increase in Serious Group A Streptococcus Infections | Zendy

Susan Rogers | Zendy; Robert J. Commons | Zendy; Margie Danchin | Zendy; Gowri Selvaraj | Zendy; Loraine Kelpie | Zendy; Nigel Curtis | Zendy; Roy M. RobinsBrowne | Zendy; Jonathan R. Carapetis | Zendy

Open Access

Strain Prevalence, Rather than Innate Virulence Potential, Is the Major Factor Responsible for an Increase in Serious Group A Streptococcus Infections

Author(s) -

Susan Rogers,

Robert J. Commons,

Margie Danchin,

Gowri Selvaraj,

Loraine Kelpie,

Nigel Curtis,

Roy M. RobinsBrowne,

Jonathan R. Carapetis

Publication year - 2007

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/513875

Subject(s) - virulence , virulence factor , microbiology and biotechnology , strain (injury) , streptococcus , biology , group a , innate immune system , streptococcus pneumoniae , immunology , medicine , bacteria , genetics , gene , antibiotics , immune system , anatomy

It is postulated that the surge in incidence and severity of group A streptococcus (GAS) infections since the 1980s is due to the emergence of strains of GAS with increased virulence. We used active, population-based surveillance of invasive GAS disease, serologically confirmed pharyngitis, and carriage to determine whether particular strains were associated with invasive disease.

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