Pneumonic Tularemia in a Patient with Chronic Granulomatous Disease
Author(s) -
Melinda C. Maranan,
Deborah Schiff,
Daniel Johnson,
Cyril Abrahams,
Mark E. Wylam,
Susan I. Gerber
Publication year - 1997
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/513777
Subject(s) - chronic granulomatous disease , tularemia , medicine , francisella tularensis , pneumonia , granuloma , granulomatous disease , disease , pathology , immunology , dermatology , biochemistry , virulence , gene , chemistry
We report the case of a 14-year-old boy with granulomatous pneumonia caused by Francisella tularensis. In addition, an autosomal recessive form of chronic granulomatous disease was diagnosed. Both F. tularensis and chronic granulomatous disease are associated with pulmonary granulomas. To our knowledge, this is the first report of F. tularensis infection in a patient with chronic granulomatous disease. The relationship between these two processes is discussed.
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