Coexistence of Hepatitis B Surface Antigen (HBsAg) and Heterologous Subtype-Specific Antibodies to HBsAg among Patients with Chronic Hepatitis B Virus Infection
Author(s) -
J.-M. Zhang,
Yuan Xu,
Xin Wang,
Y.-K. Yin,
Xianghui Wu,
X.H. Weng,
Gao Qing Lu
Publication year - 2007
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/513200
Subject(s) - hbsag , medicine , hepatitis b virus , virology , antibody , serology , antigen , hepatitis b , virus , immunology , heterologous , biology , biochemistry , gene
The coexistence of hepatitis B surface antigen (HBsAg) and antibodies to HBsAg (anti-HBs) in patients with chronic hepatitis B virus (HBV) infection has been explained by the presence of viral escape mutants. Yet, no systematic analysis of such patients has been performed. We analyzed both the HBV strains and the nature of anti-HBs in such patients.
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