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A New Direction in Understanding the Pathogenesis of Respiratory Syncytial Virus Bronchiolitis: How Real Infants Suffer
Author(s) -
John P. DeVincenzo
Publication year - 2007
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/512622
Subject(s) - bronchiolitis , pathogenesis , virus , respiratory tract , immunology , respiratory system , medicine , virology , paramyxoviridae , immune system , respiratory tract infections , pneumovirus , biology , viral disease
cine, but a failure to adhere to it may have led to fundamental misunderstandings of the pathogenesis of infant viral lower respiratory tract infections. Viral lower respiratory tract disease, particularly that caused by respiratory syncytial virus (RSV), has long been thought to be the result of an exuberant and aberrant pathogenic immune response. However, a logistically elegant and detailed study of the pathology of fatal infant RSV and influenza infec-

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