Inherited Susceptibility to Acute Pyelonephritis: A Family Study of Urinary Tract Infection | Zendy

AnnCharlotte Lundstedt | Zendy; Irene Leijonhufvud | Zendy; Bryndís Ragnarsdóttir | Zendy; Diana Karpman | Zendy; Björn Andersson | Zendy; Catharina Svanborg | Zendy

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Inherited Susceptibility to Acute Pyelonephritis: A Family Study of Urinary Tract Infection

Author(s) -

AnnCharlotte Lundstedt,

Irene Leijonhufvud,

Bryndís Ragnarsdóttir,

Diana Karpman,

Björn Andersson,

Catharina Svanborg

Publication year - 2007

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/512620

Subject(s) - acute cystitis , pedigree chart , medicine , urinary system , disease , genetic predisposition , case control study , immunology , genetics , biology , gene

Urinary tract infections (UTIs) are important causes of morbidity and death. The present study investigated whether genetic factors influence susceptibility to acute pyelonephritis (APN). CXCR1 expression was investigated as a factor predisposing to APN, because low CXCR1 expression has been associated with disease susceptibility in mice and disease-prone children.

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