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Neuraminidase Inhibitors Improve Outcome of Patients with Leukemia and Influenza: An Observational Study
Author(s) -
Roy F. Chemaly,
Harrys A. Torres,
Elizabeth Aguilera,
Gloria Mattiuzzi,
Maria E. Cabanillas,
Hagop M. Kantarjian,
Verónica GonzálezCalle,
Amar Safdar,
Issam Raad
Publication year - 2007
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/512374
Subject(s) - medicine , neuraminidase , neuraminidase inhibitor , observational study , zanamivir , pneumonia , leukemia , oseltamivir , acute leukemia , virology , virus , covid-19 , disease , infectious disease (medical specialty)
We reviewed the records of 33 patients with leukemia who experienced influenza during the period from October 2000 to March 2004. Three (38%) of the 8 patients who did not receive neuraminidase inhibitor therapy and none of the 25 patients who received it died of influenza pneumonia (P=.001). The use of neuraminidase inhibitor therapy seems to improve the outcome of influenza in patients with leukemia.

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