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Ongoing substance use is a potential confounder for immunological studies on hepatitis C virus (HCV), but there is little in the literature regarding the effects of injection drug use (IDU) or alcohol on HCV-specific immune responses. We wanted to determine whether IDU or alcohol affected immune responses in HCV-infected and human immunodeficiency virus (HIV)/HCV coinfected subjects.

Effect of Exposure to Injection Drugs or Alcohol on Antigen‐Specific Immune Responses in HIV and Hepatitis C Virus Coinfection