Severe Photosensitivity Causing Multifocal Squamous Cell Carcinomas Secondary to Prolonged Voriconazole Therapy | Zendy

Kate McCarthy | Zendy; E. Geoffrey Playford | Zendy; David Looke | Zendy; Michael Whitby | Zendy

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Severe Photosensitivity Causing Multifocal Squamous Cell Carcinomas Secondary to Prolonged Voriconazole Therapy

Author(s) -

Kate McCarthy,

E. Geoffrey Playford,

David Looke,

Michael Whitby

Publication year - 2007

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/511685

Subject(s) - medicine , voriconazole , posaconazole , photosensitivity , aspergillosis , dermatology , chronic granulomatous disease , antifungal , immunology , physics , quantum mechanics

A 32-year-old woman was treated with long-term voriconazole therapy for recurrent aspergillosis associated with chronic granulomatous disease. A short time after commencement of voriconazole therapy, a severe photosensitivity reaction developed. Continued voriconazole exposure led to the development of multifocal facial squamous cell carcinomas. The photosensitivity reaction resolved after the patient changed therapy to posaconazole.

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