Conservation of Virally Encoded MicroRNAs in Kaposi Sarcoma–Associated Herpesvirus in Primary Effusion Lymphoma Cell Lines and in Patients with Kaposi Sarcoma or Multicentric Castleman Disease
Author(s) -
Vickie Marshall,
Thomas L. Parks,
Rachel Bagni,
Cheng Dian Wang,
Mark A. Samols,
Jianhong Hu,
Kathleen M. Wyvil,
Karen Aleman,
Richard F. Little,
Robert Yarchoan,
Rolf Renne,
Denise Whitby
Publication year - 2007
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/511434
Subject(s) - primary effusion lymphoma , kaposi's sarcoma associated herpesvirus , biology , microrna , lymphoma , gene , sarcoma , virus , virology , kaposi's sarcoma , genetics , herpesviridae , immunology , viral disease , pathology , medicine , human herpesvirus
MicroRNAs are small noncoding RNAs that posttranscriptionally regulate gene expression. Kaposi sarcoma (KS)-associated herpesvirus (KSHV) encodes 12 distinct microRNA genes, all of which are located within the latency-associated region that is highly expressed in all KSHV-associated malignancies.
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