Clinical Utility of HIV Standard Genotyping among Antiretroviral-Naive Individuals with Unknown Duration of Infection | Zendy

Davey M. Smith | Zendy; Nasreen Moini | Zendy; Rick L. Pesano | Zendy; Edward R. Cachay | Zendy; Heidi Aiem | Zendy; Yolanda Lie | Zendy; D. D. Richman | Zendy; Susan J. Little | Zendy

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Clinical Utility of HIV Standard Genotyping among Antiretroviral-Naive Individuals with Unknown Duration of Infection

Author(s) -

Davey M. Smith,

Nasreen Moini,

Rick L. Pesano,

Edward R. Cachay,

Heidi Aiem,

Yolanda Lie,

D. D. Richman,

Susan J. Little

Publication year - 2007

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/510748

Subject(s) - medicine , human immunodeficiency virus (hiv) , genotyping , antiretroviral drug , drug resistance , viral load , antiretroviral treatment , antiretroviral therapy , immunology , virology , genotype , biology , genetics , gene

In clinical settings, we have found a high rate of human immunodeficiency virus (HIV) drug resistance among antiretroviral-naive patients for whom the duration of infection was unknown. These high rates were most likely the result of both transmitted resistance and informal antiretroviral use, and they suggest that routine resistance testing among antiretroviral-naive patients would be a cost-effective clinical practice.

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