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The Relationship between Previous Fluoroquinolone Use and Levofloxacin Resistance in Helicobacter pylori Infection
Author(s) -
Jennifer Carothers,
Michael G. Bruce,
Thomas W. Hennessy,
M. Bensler,
Julie Morris,
Alisa Reasonover,
Debby Hurlburt,
Alan J. Parkinson,
John M. Coleman,
Brian J. McMahon
Publication year - 2006
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/510074
Subject(s) - levofloxacin , medicine , helicobacter pylori , helicobacter pylori infection , helicobacter , ofloxacin , helicobacter infections , microbiology and biotechnology , antibacterial agent , ciprofloxacin , antibiotics , biology
The relationship between prior fluoroquinolone use and levofloxacin resistance in Helicobacter pylori infection is unknown. Among 125 enrolled patients, 8.8% had H. pylori isolates that were resistant to levofloxacin. Levofloxacin resistance was associated with any prior fluoroquinolone use over the previous 10 years and with the total number of fluoroquinolone courses prescribed (P<.001).

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