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Cyclosporin A Provides No Sustained Immunologic Benefit to Persons with Chronic HIV‐1 Infection Starting Suppressive Antiretroviral Therapy: Results of a Randomized, Controlled Trial of the AIDS Clinical Trials Group A5138
Author(s) -
Michael M. Lederman,
Laura Smeaton,
K.Y. Smith,
Benigno Rodríguez,
Minya Pu,
Hongying Wang,
Anne Sevin,
Pablo Tebas,
Scott F. Sieg,
Kathy Medvik,
David M. Margolis,
Richard B. Pollard,
Hildegund C.J. Ertl,
Hernán Valdez
Publication year - 2006
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/509261
Subject(s) - immunology , medicine , immune system , clinical trial , randomized controlled trial , regimen , maraviroc , immunopathology , chronic infection , human immunodeficiency virus (hiv)
Although the determinants of immune deficiency and immune restoration in chronic human immunodeficiency virus (HIV)-1 infection are not well understood, immune activation has been proposed as being central to the pathogenesis of HIV.

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